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Follow-up consultations are required every six months for active treatment plans and every nine months for maintenance dosing

A later study showed MOTS-c is also exercise-induced: levels rise sharply in muscle and blood during physical activity, and treated older mice nearly doubled their running capacity (Reynolds et al., 2021, Nature Communications)

Birth Defects Research Part A: Clinical and Molecular Teratology

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It does not fade spontaneously and does not respond to time alone